
The game features a companion perk, called Miss Fortune, which applies a variety of debuffs and fatigue damage to the target, rather than killing them outright. Player weapons that deal area of effect damage can affect the Stranger, but he cannot be killed.

Furthermore, as the Stranger dies not use a script, but is an actual NPC spawned by the game with a functioning weapon, it's possible for him to spawn stuck in a wall, submerged in water, or otherwise placed in a position where all six shots will miss or he will kill the player (if he spawns in a way that places the player in his line of fire). Note that Grim Reaper's Sprint will not activate if the Mysterious Stranger appears, as they're dependent on the player character dealing the killing blow. The game keeps track of the visits and will list them under the Stats/General tab in the Pip-Boy 3000. One shot is enough to kill any enemy, but the Stranger will always fire all six shots for a potential 108 012 points of damage.

44 Magnum revolver into the target, dealing 18 002 of damage (9 001 base + 9 001 critical damage at 100% multiplier) per shot.

When the Mysterious ally appears in all his trenchcoat and fedora glory, he will empty his. The perk activates a 10% chance for the Stranger to appear whenever they are using V.A.T.S.
